The biotechnology industry, which uses renewable that includes cultivation, transport, and contract manufac-turing, all aimed at increasing productivity and reducing the cost of biobased products. The application of this technol-ogy holds great promise for the development of bio-based products, including alternatives to petroleum and pharma-ceuticals.In June 2020, Japan's Cabinet Office formulated the "Bio Strategy 2020" with the ambitious goal of expanding the market size of high-performance biomaterials, bioplas-tics, bioproduction systems, and more to 53.3 trillion yen by 2030.Based on this strategy, NEDO launched a public call for proposals in 2021 for the "Development of Production Tech-nology for Bio-derived Products to Accelerate Carbon Re-cycling - Biofoundry Infrastructure Technology Development for Production Processes" (Biofoundry Project). The goal of this project is to establish the necessary development in-frastructure for biomanufacturing processes, facilitate the validation of biomanufacturing in academia and industry, and promote expertise in biomanufacturing. A budget of 5.4 billion yen has been allocated over six years starting in 2021 to establish a platform in the field of bio-refinery.GEI, which was selected through this open call, is a ven-ture founded in 2011. Among biomass derived from agricul-tural crops and plants, their business focus on amino acid and carbon-neutral biofuels made from plant stems and leaves, which can be used as feed additives and food addi-tives, and which do not compete with food or feed. The goal Source: GEI News Release on December 27, 2022Location of the completed NEDO Biofoundry FacilityBiofoundry Institute Building (End of 2022)46biological resources and more, is expected to grow to 200 trillion yen worldwide by 2030. Among the burgeoning sectors, a prominent growth area is "biomanufacturing," which involves the production of substances using cells from living organisms. At the forefront of biomanufacturing is the Biofoundry Institute, which opened in June. This institute was established through cooperation between the New Energy and Industrial Technology Development Or-ganization (NEDO) and the Green Earth Institute (GEI). It is located at the Mitsui Chemicals Mobara Plant in Mobara City, Chiba Prefecture, Japan. This facility fa-cilitates the targeted improvement of microbial pro-duction capabilities and enables the verification of scale-up processes in bioreactors up to 3000 L. The Institute is actively seeking collaborations with com-panies, universities, and research institutions for the validation of bioproduction processes. The goal is to bridge the gap from pre-processing to refinement, thereby promoting the practical use of products. A tour and inauguration ceremony were held at the fa-cility on June 1.Biotechnology market to grow to ¥53.3 trillion by 2030The term "biofoundry" refers to a biomanufacturing system New Energy and Industrial Technology Development Organization (NEDO)Biofoundry capable of scale-up verification begins full-scale operation
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